SCHEMBL14727795

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14474036	0.94	CYP1A2 (0.52)	CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL14474102	0.92	CYP1A2 (0.60)	CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL14475191	0.91	CYP1A2 (0.58)	CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL2155634	0.90	CYP1A2 (0.55)	CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL2155193	0.89	CYP1A2 (0.56)	CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL14475858	0.89	CLK4 (0.53)	CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL2155059	0.89	MAPT (0.47)	CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL18023053	0.89	CYP1A2 (0.55)	CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL14731294	0.88	CYP1A2 (0.54)	CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL14475909	0.87	CYP1A2 (0.61)	CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.