SCHEMBL14728124

SCHEMBL14728124

CCn1c2ccccc2c2cc3c4ccc(N(c5ccccc5)c5ccc6c(c5)C(C)(C)c5ccccc5-6)cc4c4ccccc4c3cc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
KDM4E B2RXH2 5/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
MAPK1 P28482 3/20 0.38
ALDH1A1 P00352 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
HTT P42858 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
HBB P68871 1/20 0.38
LMNA P02545 3/20 0.37
KDM1A O60341 1/20 0.36
NPY5R Q15761 4/20 0.35
POLB P06746 3/20 0.35
BLM P54132 1/20 0.35
RORC P51449 1/20 0.34
PKM P14618 1/20 0.34
CASP1 P29466 1/20 0.34
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14728117 0.95 NPY5R (0.36) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL14728119 0.89 MAPT (0.34) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL16202909 0.86 KDM4E (0.37) KDM4E
SCHEMBL15306092 0.86 PDK2 (0.39) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL14728107 0.86 KDM4E (0.49) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL14728176 0.86 KDM4E (0.37) KDM4E
SCHEMBL15306336 0.84 PDK2 (0.40) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL24022285 0.83 KDM1A (0.40) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL14466326 0.83 MAPT (0.45) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL13634124 0.83 MAPT (0.45) MAPTKDM4EMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME PPOX, ORC3, CACNA2D3 MAPT 589/4885KDM4E 1626/4885MEN1 1579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.