SCHEMBL14728140

SCHEMBL14728140

c1ccc(N(c2ccccc2)c2ccc(-c3ccc4c(c3)c3ccccc3c3cc5c(cc43)c3ccccc3n5-c3ccccc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.47
KDM4E B2RXH2 3/20 0.47
ATM Q13315 1/20 0.47
TSPO P30536 3/20 0.38
HDAC4 P56524 1/20 0.35
PTGER4 P35408 1/20 0.34
KMT2A Q03164 2/20 0.33
MAPK8 P45983 1/20 0.33
IL1R1 P14778 1/20 0.33
ALDH1A1 P00352 3/20 0.32
MAPT P10636 2/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.31
CYP1A2 P05177 2/20 0.30
CYP3A4 P08684 2/20 0.30
CYP2C9 P11712 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18716752 0.95 L3MBTL1 (0.43) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL15179853 0.95 L3MBTL1 (0.50) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL12153492 0.95 L3MBTL1 (0.50) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL15179856 0.95 L3MBTL1 (0.50) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL15179743 0.95 L3MBTL1 (0.50) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL15180066 0.95 L3MBTL1 (0.50) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL12196082 0.93 L3MBTL1 (0.51) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL14728158 0.92 L3MBTL1 (0.45) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL14728151 0.92 L3MBTL1 (0.45) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL15179817 0.92 L3MBTL1 (0.47) L3MBTL1KDM4EATMTSPOHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME PPOX, ORC3, CACNA2D3 L3MBTL1 2318/4885KDM4E 1626/4885ATM 4087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.