SCHEMBL14728155

SCHEMBL14728155

c1ccc(-c2ccc(N(c3ccc4c(c3)c3ccccc3c3cc5c(cc43)c3ccccc3n5-c3ccccc3)c3cccc4ccccc34)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
TSPO P30536 1/20 0.31
HDAC4 P56524 1/20 0.31
KMT2A Q03164 2/20 0.30
IL1R1 P14778 1/20 0.30
PTGER4 P35408 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14728183 0.94 KDM4E (0.42) L3MBTL1KDM4EATM
SCHEMBL14728150 0.92 KDM4E (0.44) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL26058887 0.91 L3MBTL1 (0.41) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL12242934 0.91 L3MBTL1 (0.45) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL13725082 0.91 L3MBTL1 (0.45) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL15179819 0.90 KDM4E (0.38) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL15179896 0.90 KDM4E (0.38) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL14728185 0.90 KDM4E (0.40) L3MBTL1KDM4EATM
SCHEMBL19152186 0.90 L3MBTL1 (0.42) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL19533760 0.90 L3MBTL1 (0.44) L3MBTL1KDM4EATMTSPOHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME PPOX, ORC3, CACNA2D3 L3MBTL1 2318/4885KDM4E 1626/4885ATM 4087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.