Sugi Predict

Sugi Predict / Compounds / SCHEMBL14728174

SCHEMBL14728174

SCHEMBL14728174

c1ccc(-c2ccc(-n3c4ccccc4c4cc5c6ccc(N(c7ccccc7)c7ccccc7)cc6c6ccccc6c5cc43)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ ATM Q13315 1/20 0.42
▸ HDAC4 P56524 1/20 0.37
▸ TSPO P30536 1/20 0.34
▸ KMT2A Q03164 2/20 0.32
▸ IL1R1 P14778 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ RAC2 P15153 1/20 0.31
▸ RAC3 P60763 1/20 0.31
▸ CDC42 P60953 1/20 0.31
▸ RAC1 P63000 1/20 0.31
▸ AKR1C4 P17516 1/20 0.31
▸ AKR1C3 P42330 1/20 0.31
▸ AKR1C2 P52895 1/20 0.31
▸ AKR1C1 Q04828 1/20 0.31
▸ PTPN1 P18031 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14728184 0.99 L3MBTL1 (0.44) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL14728154 0.96 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL18688709 0.95 L3MBTL1 (0.45) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL20274691 0.95 L3MBTL1 (0.45) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL18716752 0.94 L3MBTL1 (0.43) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL24029427 0.93 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL15894183 0.93 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL21974341 0.93 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL17943400 0.93 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL16773297 0.92 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9917262-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-13 — — US disclosed
US-9917262-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-13 — — US disclosed
US-20160133853-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LT.D (KR) 2016-05-12 — — US disclosed
US-20160133853-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LT.D (KR) 2016-05-12 — — US disclosed
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 — — US disclosed
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 — — US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 — — US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME PPOX, ORC3, CACNA2D3 L3MBTL1 2318/4885KDM4E 1626/4885ATM 4087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.