SCHEMBL14728178

SCHEMBL14728178

c1ccc(-n2c3ccccc3c3cc4c5ccc(-c6cccc(-c7cccc8c7sc7ccccc78)c6)cc5c5ccccc5c4cc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.46
PRKDC P78527 3/20 0.39
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PARP14 Q460N5 1/20 0.32
DNPH1 O43598 1/20 0.32
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
F9 P00740 1/20 0.32
PIK3CD O00329 1/20 0.31
BRD4 O60885 1/20 0.31
PIK3CA P42336 1/20 0.31
PIK3CB P42338 1/20 0.31
MTOR P42345 1/20 0.31
PIK3CG P48736 1/20 0.31
KCNH2 Q12809 1/20 0.31
BRDT Q58F21 1/20 0.31
HSD17B10 Q99714 1/20 0.31
LIMK1 P53667 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15959692 0.97 ALOX5 (0.49) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL14728165 0.95 ALOX5 (0.44) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL18804969 0.94 ALOX5 (0.48) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL15959736 0.93 ALOX5 (0.46) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL15959675 0.92 ALOX5 (0.49) ALOX5PRKDCPARP14DNPH1TNKS
SCHEMBL18505197 0.92 ALOX5 (0.49) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL15959758 0.92 ALOX5 (0.49) ALOX5PRKDCPARP14DNPH1TNKS
SCHEMBL17661335 0.92 ALOX5 (0.51) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL896668 0.92 ALOX5 (0.51) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL10165755 0.92 ALOX5 (0.51) ALOX5PRKDCKDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME PPOX, ORC3, CACNA2D3 ALOX5 2041/4885PRKDC 556/4885KDM4E 1626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.