Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | RARG | P13631 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FSHR | P23945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728397 | 0.95 | MAPT (0.42) | KMT2AMAPTALDH1A1MEN1ACHE | |
| SCHEMBL14728392 | 0.85 | PTGS1 (0.37) | KMT2AMAPTPPARGALDH1A1NCOA2 | |
| SCHEMBL10596262 | 0.76 | KMT2A (0.58) | KMT2AMAPTPPARGALDH1A1NCOA2 | |
| SCHEMBL13668364 | 0.75 | KMT2A (0.48) | KMT2AMAPTALDH1A1RXRARXRB | |
| SCHEMBL12578478 | 0.73 | TP53 (0.39) | KMT2AMAPTPPARGALDH1A1RXRA | |
| SCHEMBL9523050 | 0.72 | RXRA (0.50) | PPARGRXRARXRBRXRGRARB | |
| SCHEMBL7804011 | 0.72 | RXRA (0.42) | PPARGALDH1A1RXRARXRBRXRG | |
| SCHEMBL8151081 | 0.72 | RXRA (0.42) | PPARGALDH1A1RXRARXRBRXRG | |
| SCHEMBL14999386 | 0.72 | RXRA (0.34) | KMT2ARXRARXRBRXRGRARB | |
| SCHEMBL17956595 | 0.71 | MEN1 (0.45) | KMT2AMAPTALDH1A1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8669315-B2 | Polycarbonate compositions and methods for the manufacture and use thereof | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-03-11 | — | — | US | disclosed |
| US-20130053487-A1 | POLYCARBONATE COMPOSITIONS AND METHODS FOR THE MANUFACTURE AND USE THEREOF | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-02-28 | — | — | US | disclosed |