Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728396 | 0.95 | KMT2A (0.39) | MAPTTDP1LMNAALDH1A1MEN1 | |
| SCHEMBL14728392 | 0.81 | PTGS1 (0.37) | MAPTTDP1ELANEALDH1A1MEN1 | |
| SCHEMBL13712347 | 0.79 | SMN1; SMN2 (0.45) | MAPTLMNACYP3A4ALDH1A1MEN1 | |
| Acetic Acid Phenyl Ester SCHEMBL27799621 | 0.74 | ELANE (0.64) | MAPTTDP1LMNACYP3A4ELANE | |
| SCHEMBL10596262 | 0.72 | KMT2A (0.58) | MAPTTDP1LMNACYP3A4ALDH1A1 | |
| SCHEMBL12418593 | 0.72 | RXRA (0.58) | LMNACYP3A4ALDH1A1USP2KDM4E | |
| SCHEMBL9523050 | 0.72 | RXRA (0.50) | CYP3A4 | |
| SCHEMBL8151081 | 0.71 | RXRA (0.42) | LMNACYP3A4ALDH1A1 | |
| SCHEMBL7804011 | 0.71 | RXRA (0.42) | LMNACYP3A4ALDH1A1 | |
| Acetic Acid Phenyl Ester SCHEMBL8080259 | 0.71 | ELANE (0.64) | MAPTTDP1LMNACYP3A4ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8669315-B2 | Polycarbonate compositions and methods for the manufacture and use thereof | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-03-11 | — | — | US | disclosed |
| US-20130053487-A1 | POLYCARBONATE COMPOSITIONS AND METHODS FOR THE MANUFACTURE AND USE THEREOF | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-02-28 | — | — | US | disclosed |