SCHEMBL147290

SCHEMBL147290

Brc1cccc2[nH]ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 1.00
PARP1 P09874 1/20 0.55
NOS1 P29475 1/20 0.47
AXL P30530 1/20 0.47
RHEB Q15382 9/20 0.46
PIK3CD O00329 1/20 0.46
MAPK1 P28482 1/20 0.43
ADRB1 P08588 1/20 0.43
HTR6 P50406 1/20 0.43
MAPK14 Q16539 1/20 0.42
PRKCI P41743 1/20 0.42
TRPA1 O75762 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
ITGB2 P05107 1/20 0.41
ICAM1 P05362 1/20 0.41
ITGAL P20701 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
ADK P55263 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29507024 1.00 AHR (1.00) AHRPARP1NOS1AXLRHEB
Tert-Butyl Formate SCHEMBL27708218 0.80 AHR (0.64) AHRPARP1NOS1AXLRHEB
SCHEMBL15741379 0.80 AHR (0.64) AHRPARP1NOS1AXLRHEB
SCHEMBL20540332 0.75 PIK3CD (0.64) AHRRHEBPIK3CDMAPK1ADRB1
SCHEMBL879761 0.73 AHR (0.58) AHRRHEBPIK3CDMAPK1ADRB1
SCHEMBL3335002 0.73 AHR (0.58) AHRNOS1RHEBPIK3CDMAPK1
SCHEMBL5720513 0.73 AHR (0.57) AHRRHEBPIK3CDMAPK1ADRB1
SCHEMBL30681623 0.73 AHR (0.57) AHRRHEBPIK3CDMAPK1ADRB1
SCHEMBL113992 0.71 AHR (0.56) AHRPARP1RHEBPIK3CDMAPK1
SCHEMBL10718362 0.71 AHR (0.56) AHRRHEBPIK3CDMAPK1ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1554 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109670-A1 METHOD FOR ARYL DEBROMINATION AND ACYLATION OF BROMINATED BENZO-FUSED NITROGEN HETEROCYCLE Shanghai OuChem Bio-Technology Co., LTD (CN) 2026-04-23 US claimed
CN-119857098-A Application of indole triazole derivative in preparation of drug-resistant candida albicans drug 云南中医药大学 2025-04-22 CN claimed
EP-4526426-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS Danmarks Tekniske Universitet (DK) 2025-03-26 EP claimed
CN-119059958-A Method for aryl debromination acylation of bromobenzazepine compounds 上海沃凯生物技术有限公司 2024-12-03 CN claimed
CN-115215782-B Preparation method of 4-bromoindole 常州琦诺生物科技有限公司 2024-09-03 CN claimed
CN-118125960-A Bisindole 3-ketone compound, application and preparation method thereof 云南农业大学 2024-06-04 CN claimed
CN-117886736-A 2-indolyl-3-imine indoline derivative, preparation method and application thereof 苏州昊帆生物股份有限公司 2024-04-16 CN claimed
CN-115160584-B Heterogeneous pore supermolecule organic framework constructed based on synergistic effect of cations-pi and static electricity and preparation method 西北工业大学 2024-03-22 CN claimed
WO-2023222879-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS DANMARKS TEKNISKE UNIVERSITET (DK) 2023-11-23 WO claimed
CN-116283971-A Indoline compound containing condensed heterocyclic structure, and preparation method and application thereof 沈阳药科大学 2023-06-23 CN claimed
CN-1665849-A Halogenated catalyst system for olefin polymerization UNIVATION TECHNOLOGIES (US) 2005-09-07 CN claimed
CN-1665850-A Heterocyclic nitrogen-containing activators and catalyst systems for olefin polymerization UNIVATION TECHNOLOGIES (US) 2005-09-07 CN claimed
US-6930070-B2 Heterocyclic nitrogen-containing activators and catalyst systems for olefin polymerization UNIVATION TECHNOLOGIES, LLC (US) 2005-08-16 US claimed
US-20050075242-A1 Heterocyclic nitrogen-containing activators and catalyst systems for olefin polymerization UNIVATION TECHNOLOGIES, LLC 2005-04-07 US claimed
EP-1517931-A1 HALOGEN SUBSTITUTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION Univation Technologies, LLC (US) 2005-03-30 EP claimed
EP-1517932-A2 HETEROCYCLIC NITROGEN-CONTAINING ACTIVATORS AND CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION Univation Technologies LLC (US) 2005-03-30 EP claimed
CN-1544419-A N-substituted indole derivative preparation method 中国海洋大学 2004-11-10 CN claimed
US-20040127348-A1 Halogen substituted catalyst system for olefin polymerization UNIVATION TECHNOLOGIES, LLC 2004-07-01 US claimed
WO-2004003037-A1 HALOGEN SUBSTITUTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC. (US) 2004-01-08 WO claimed
WO-2004003032-A2 HETEROCYCLIC NITROGEN-CONTAINING ACTIVATORS AND CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC (US) 2004-01-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050075242-A1 Heterocyclic nitrogen-containing activators and catalyst systems for olefin polymerization NBAS, NIT2, MYB AHR 164/4885PARP1 1052/4885NOS1 199/4885
US-20260109670-A1 METHOD FOR ARYL DEBROMINATION AND ACYLATION OF BROMINATED BENZO-FUSED NITROGEN HETEROCYCLE NAT1, AADAC, NAA15 AHR 33/4885PARP1 1258/4885NOS1 496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.