SCHEMBL14729280

SCHEMBL14729280

O=C(O)CC[C@H](NC(=O)C[C@H](NC(=O)OCc1ccccc1)C(=O)O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 6/20 0.61
MME P08473 1/20 0.57
ECE1 P42892 1/20 0.57
NAALAD2 Q9Y3Q0 1/20 0.53
CASP1 P29466 4/20 0.52
PPARG P37231 1/20 0.51
PPARA Q07869 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18145506 1.00 FOLH1 (0.61) FOLH1MMEECE1NAALAD2CASP1
SCHEMBL19925534 0.92 FOLH1 (0.64) FOLH1MMEECE1NAALAD2CASP1
SCHEMBL19307785 0.92 FOLH1 (0.64) FOLH1MMEECE1NAALAD2CASP1
SCHEMBL9698236 0.92 FOLH1 (0.64) FOLH1MMEECE1NAALAD2CASP1
SCHEMBL9697060 0.92 FOLH1 (0.64) FOLH1MMEECE1NAALAD2CASP1
SCHEMBL24238520 0.92 FOLH1 (0.64) FOLH1MMEECE1NAALAD2CASP1
SCHEMBL910233 0.92 FOLH1 (0.70) FOLH1MMEECE1NAALAD2CASP1
SCHEMBL910423 0.92 FOLH1 (0.70) FOLH1MMEECE1NAALAD2CASP1
SCHEMBL910232 0.92 FOLH1 (0.70) FOLH1MMEECE1NAALAD2CASP1
Benzene SCHEMBL28226069 0.92 FOLH1 (0.70) FOLH1MMEECE1NAALAD2CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 US disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 US disclosed
US-20240409580-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-12 US disclosed
US-12139554-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-11-12 US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-20180258134-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2018-09-13 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MME 157/4885ECE1 1285/4885
US-20180258134-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MME 157/4885ECE1 1285/4885
US-20240409580-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MME 157/4885ECE1 1285/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 FOLH1 4/4885MME 772/4885ECE1 2929/4885
US-12139554-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MME 157/4885ECE1 1285/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MME 157/4885ECE1 1285/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 FOLH1 4/4885MME 842/4885ECE1 3368/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MME 157/4885ECE1 1285/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MME 157/4885ECE1 1285/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MME 157/4885ECE1 1285/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MME 157/4885ECE1 1285/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MME 157/4885ECE1 1285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.