Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.70 |
| ▸ | MME | P08473 | 1/20 | 0.64 |
| ▸ | ECE1 | P42892 | 1/20 | 0.64 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.61 |
| ▸ | PPARA | Q07869 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28226069 | 1.00 | FOLH1 (0.70) | FOLH1MMEECE1NAALAD2PPARA | |
| SCHEMBL910232 | 1.00 | FOLH1 (0.70) | FOLH1MMEECE1NAALAD2PPARA | |
| SCHEMBL910233 | 1.00 | FOLH1 (0.70) | FOLH1MMEECE1NAALAD2PPARA | |
| Cyclopropane SCHEMBL5691187 | 0.96 | FOLH1 (0.65) | FOLH1MMEECE1NAALAD2PPARA | |
| SCHEMBL24238520 | 0.95 | FOLH1 (0.64) | FOLH1MMEECE1NAALAD2PPARA | |
| SCHEMBL9697060 | 0.95 | FOLH1 (0.64) | FOLH1MMEECE1NAALAD2PPARA | |
| SCHEMBL19925534 | 0.95 | FOLH1 (0.64) | FOLH1MMEECE1NAALAD2PPARA | |
| SCHEMBL19307785 | 0.95 | FOLH1 (0.64) | FOLH1MMEECE1NAALAD2PPARA | |
| SCHEMBL9697579 | 0.95 | MME (0.65) | FOLH1MMEECE1NAALAD2CASP1 | |
| SCHEMBL9698236 | 0.95 | FOLH1 (0.64) | FOLH1MMEECE1NAALAD2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116642980-A | Method for preparing microcystin imprinting material by plasma polymerization and application | 临沂大学 | 2023-08-25 | — | — | CN | claimed |
| CN-112557572-B | Method for detecting isomer content in Cbz-Glu | 成都普康生物科技有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-108290919-B | Azithromycin derivatives having epithelial barrier enhancing properties | 艾比恩多制药有限责任公司 | 2022-06-17 | — | — | CN | claimed |
| US-10723752-B2 | Azithromycin derivatives with epithelial barrier enhancement properties | EPIENDO PHARMACEUTICALS EHF (IS) | 2020-07-28 | — | — | US | claimed |
| US-20180354981-A1 | Azithromycin Derivatives With Epithelial Barrier Enhancement Properties | EPI-ENDO PHARMACEUTICALS EHF (IS) | 2018-12-13 | — | — | US | claimed |
| EP-0550899-B1 | Process for preparing derivatives of (R) 5-pentylamino-5-oxopentanoic acid with anticholecystokinin activity | ROTTA RESEARCH LAB (IT) | 1995-12-06 | — | — | EP | claimed |
| EP-0498830-B1 | GLUTAMIC AND ASPARTIC ACID DERIVATIVES WITH ANTIGASTRIN ACTIVITY AND A METHOD FOR THEIR PREPARATION | ROTTA RESEARCH LAB (IT) | 1994-12-14 | — | — | EP | claimed |
| EP-0561863-B1 | AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY | ROTTA RESEARCH LAB (IT) | 1994-11-02 | — | — | EP | claimed |
| EP-0561863-A1 | AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY. | ROTTA RESEARCH LAB (IT) | 1993-09-29 | — | — | EP | claimed |
| EP-0550899-A1 | Process for preparing derivatives of (R) 5-pentylamino-5-oxopentanoic acid with anticholecystokinin activity | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1993-07-14 | — | — | EP | claimed |
| EP-0498830-A1 | GLUTAMIC AND ASPARTIC ACID DERIVATIVES WITH ANTIGASTRIN ACTIVITY AND A METHOD FOR THEIR PREPARATION. | ROTTA RESEARCH LAB (IT) | 1992-08-19 | — | — | EP | claimed |
| US-5130474-A | For treatment of gastrointestinal disorders such as colitis, pancreatitis, antispastic agents and biliary diskinesia | ROTTA RESEARCH LABORATORIUM SPA (IT) | 1992-07-14 | — | — | US | claimed |
| WO-1992010479-A1 | AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1992-06-25 | — | — | WO | claimed |
| WO-1991006529-A1 | GLUTAMIC AND ASPARTIC ACID DERIVATIVES WITH ANTIGASTRIN ACTIVITY AND A METHOD FOR THEIR PREPARATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1991-05-16 | — | — | WO | claimed |
| EP-0344184-A1 | DERIVATIVES OF (R) 5-PENTYLAMINO-5-OXOPENTANOIC ACID WITH ANTICHOLECYSTOKININ ACTIVITY. | ROTTA RESEARCH LAB (IT) | 1989-12-06 | — | — | EP | claimed |
| WO-1988005774-A1 | DERIVATIVES OF (R) 5-PENTYLAMINO-5-OXOPENTANOIC ACID WITH ANTICHOLECYSTOKININ ACTIVITY | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1988-08-11 | — | — | WO | claimed |
| US-20260021190-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | MERCK SHARP & DOHME LLC (US) | 2026-01-22 | — | — | US | disclosed |
| EP-4615487-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | Merck Sharp & Dohme LLC (US) | 2025-09-17 | — | — | EP | disclosed |
| US-4678800-A | INHIBITORS OF ANGIOTENSIN-CONVERTING ENZYME | CIBA-GEIGY CORPORATION (US) | 1987-07-07 | — | — | US | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021190-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | INSR, GPR119, GLP1R | FOLH1 368/4885MME 449/4885ECE1 2437/4885 |
| US-20180354981-A1 | Azithromycin Derivatives With Epithelial Barrier Enhancement Properties | CFTR, AQP1, CTSA | FOLH1 3638/4885MME 587/4885ECE1 120/4885 |
| US-10723752-B2 | Azithromycin derivatives with epithelial barrier enhancement properties | CFTR, AQP1, CTSA | FOLH1 3638/4885MME 587/4885ECE1 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.