SCHEMBL910233

SCHEMBL910233

O=C(O)CC[C@H](NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 6/20 0.70
MME P08473 1/20 0.64
ECE1 P42892 1/20 0.64
NAALAD2 Q9Y3Q0 1/20 0.61
PPARA Q07869 2/20 0.57
PPARG P37231 1/20 0.57
SIRT2 Q8IXJ6 1/20 0.56
SIRT1 Q96EB6 1/20 0.56
CASP1 P29466 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28226069 1.00 FOLH1 (0.70) FOLH1MMEECE1NAALAD2PPARA
SCHEMBL910232 1.00 FOLH1 (0.70) FOLH1MMEECE1NAALAD2PPARA
SCHEMBL910423 1.00 FOLH1 (0.70) FOLH1MMEECE1NAALAD2PPARA
Cyclopropane SCHEMBL5691187 0.96 FOLH1 (0.65) FOLH1MMEECE1NAALAD2PPARA
SCHEMBL24238520 0.95 FOLH1 (0.64) FOLH1MMEECE1NAALAD2PPARA
SCHEMBL9697060 0.95 FOLH1 (0.64) FOLH1MMEECE1NAALAD2PPARA
SCHEMBL19925534 0.95 FOLH1 (0.64) FOLH1MMEECE1NAALAD2PPARA
SCHEMBL9698236 0.95 FOLH1 (0.64) FOLH1MMEECE1NAALAD2PPARA
SCHEMBL9697579 0.95 MME (0.65) FOLH1MMEECE1NAALAD2CASP1
SCHEMBL19307785 0.95 FOLH1 (0.64) FOLH1MMEECE1NAALAD2PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031663-A Erythrocyte-like artificial oxygen carrier therapeutic agent and preparation method and application thereof 南京鼓楼医院 2026-05-15 CN claimed
CN-119930561-A Raltitrexed initial raw material reference substance impurity as well as preparation method and application thereof 江苏天士力帝益药业有限公司 2025-05-06 CN claimed
CN-112557572-B Method for detecting isomer content in Cbz-Glu 成都普康生物科技有限公司 2023-05-05 CN claimed
CN-115160430-B Synthesis method of main chain segment of cable Ma Lutai 成都普康唯新生物科技有限公司 2023-05-05 CN claimed
CN-110317258-B New polypeptide fragment of somaglutide and preparation method thereof 齐鲁制药有限公司 2023-03-17 CN claimed
CN-115594736-A Bionic nano-medicament for improving curative effect of radiotherapy and chemotherapy, preparation method and application thereof 南京脑科医院(CN) 2023-01-13 CN claimed
CN-114133398-B Amino acid substituted acyclovir tricyclic nucleoside derivative and synthesis method and application thereof 中南民族大学 2022-11-22 CN claimed
CN-115160430-A Synthesis method of somaglutide backbone fragment 成都普康唯新生物科技有限公司 2022-10-11 CN claimed
CN-114133398-A Amino acid substituted acyclovir tricyclic nucleoside derivative and synthesis method and application thereof 中南民族大学 2022-03-04 CN claimed
US-11186541-B2 Potent inhibitors of aspartate N-acetyl-transferase for the treatment of Canavan disease THE UNIVERSITY OF TOLEDO (US) 2021-11-30 US claimed
EP-2255780-A1 PARAKERATOSIS INHIBITOR, PORE SHRINKING AGENT OR AGENT FOR PREVENTING OR IMPROVING ROUGH SKIN, AND COMPOSITION FOR EXTERNAL USE ON THE SKIN CONTAINING THE SAME Shiseido Company, Ltd. (JP) 2010-12-01 EP claimed
US-6398857-B1 ACCUSTIC PIEZOELECTRIC; HOT MELT INK JET PRINTING; BENZOIC ACID VEHICLE; ALKYL OR PHENYL CARBOXYLIC ACID VISCOSITY MODIFIER; RETAINS DESIRED HARDNESS XEROX CORPORATION 2002-06-04 US claimed
US-6395077-B1 INKS WITH BENZOYLBENZOIC ACID AND COLORS XEROX CORPORATION 2002-05-28 US claimed
US-5990266-A Degradable polyesters, a mixed culture of microorganisms for degrading these polyesters, and methods for making these substances UNIVERSITY OF NEBRASKA (US) 1999-11-23 US claimed
WO-1999028366-A1 DEGRADABLE POLYESTERS BOARD OF REGENTS OF UNIVERSITY OF NEBRASKA (US) 1999-06-10 WO claimed
EP-0624599-B1 Derivatives of mono (6-amino-desoxy)cyclodextrin substituted in position 6 with an alpha aminoacid group, process of their preparation and applications OREAL (FR) 1997-07-30 EP claimed
EP-0624599-A2 Derivatives of mono (6-amino-desoxy)cyclodextrin substituted in position 6 with an alpha aminoacid group, process of their preparation and applications L'OREAL (FR) 1994-11-17 EP claimed
WO-1993005046-A1 AMINODIESTERS OF RAPAMYCIN AMERICAN HOME PRODUCTS CORPORATION (US) 1993-03-18 WO claimed
US-5162333-A Treating transplantation rejection, autoimmune diseases, antiinflammatory AMERICAN HOME PRODUCTS CORPORATION (US) 1992-11-10 US claimed
EP-0292228-A2 Protecting groups for asparagine and glutamine in peptide synthesis MILLIPORE CORPORATION (US) 1988-11-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11186541-B2 Potent inhibitors of aspartate N-acetyl-transferase for the treatment of Canavan disease GOT1, ACAT1, GOT2 FOLH1 281/4885MME 613/4885ECE1 896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.