SCHEMBL14729307

SCHEMBL14729307

CN(C(=O)CCCC(=O)O)[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.41
GABRP O00591 2/20 0.41
GABRD O14764 2/20 0.41
GABRA1 P14867 2/20 0.41
GABRB1 P18505 2/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
GABRA5 P31644 2/20 0.41
GABRA3 P34903 2/20 0.41
GABRA2 P47869 2/20 0.41
GABRB2 P47870 2/20 0.41
GABRA4 P48169 2/20 0.41
GABRE P78334 2/20 0.41
GABRA6 Q16445 2/20 0.41
GABRG1 Q8N1C3 2/20 0.41
GABRG3 Q99928 2/20 0.41
GABRQ Q9UN88 2/20 0.41
CYP1A2 P05177 2/20 0.41
FOLH1 Q04609 3/20 0.40
FFAR4 Q5NUL3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18145619 1.00 SLC22A6 (0.41) SLC22A6GABRPGABRDGABRA1GABRB1
SCHEMBL14719877 0.86 CYP1A2 (0.41) CYP1A2FOLH1KDM4CTSHR
SCHEMBL20299817 0.85 FFAR4 (0.51) SLC22A6FFAR4FFAR1KDM4CPHF8
SCHEMBL28321636 0.85 FFAR4 (0.51) SLC22A6FFAR4FFAR1KDM4CPHF8
SCHEMBL13840850 0.84 GABRP (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL8670720 0.81 GABRP (0.41) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL9085224 0.81 GRM8 (0.60) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL18030268 0.81 GRM8 (0.60) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL9085219 0.81 GRM8 (0.60) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL15921817 0.80 CYP1A2 (0.46) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 US disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 US disclosed
US-20240409580-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-12 US disclosed
US-12139554-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-11-12 US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-20180258134-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2018-09-13 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 SLC22A6 937/4885GABRP 757/4885GABRD 2695/4885
US-20180258134-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 SLC22A6 937/4885GABRP 757/4885GABRD 2695/4885
US-20240409580-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 SLC22A6 937/4885GABRP 757/4885GABRD 2695/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 SLC22A6 127/4885GABRP 1506/4885GABRD 2702/4885
US-12139554-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 SLC22A6 937/4885GABRP 757/4885GABRD 2695/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 SLC22A6 937/4885GABRP 757/4885GABRD 2695/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 SLC22A6 180/4885GABRP 1590/4885GABRD 2859/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 SLC22A6 937/4885GABRP 757/4885GABRD 2695/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 SLC22A6 937/4885GABRP 757/4885GABRD 2695/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 SLC22A6 937/4885GABRP 757/4885GABRD 2695/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 SLC22A6 937/4885GABRP 757/4885GABRD 2695/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 SLC22A6 937/4885GABRP 757/4885GABRD 2695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.