SCHEMBL14719877

SCHEMBL14719877

CCOC(=O)CCCC(=O)N(C)C(CCC(=O)O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
FOLH1 Q04609 2/20 0.40
POLB P06746 1/20 0.39
ALOX5 P09917 1/20 0.36
KMT2A Q03164 2/20 0.36
TSHR P16473 1/20 0.36
PAM P19021 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
NR1I2 O75469 1/20 0.35
PGR P06401 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
PTGS2 P35354 1/20 0.35
PDE4D Q08499 1/20 0.35
RAB9A P51151 1/20 0.35
KDM5A P29375 1/20 0.34
KDM4C Q9H3R0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18145619 0.86 SLC22A6 (0.41) CYP1A2FOLH1TSHRKDM4C
SCHEMBL14729307 0.86 SLC22A6 (0.41) CYP1A2FOLH1TSHRKDM4C
SCHEMBL20299817 0.79 FFAR4 (0.51) KMT2ATSHRKDM5AKDM4C
SCHEMBL28321636 0.79 FFAR4 (0.51) KMT2ATSHRKDM5AKDM4C
SCHEMBL18145528 0.75 POLB (0.39) CYP1A2POLBALOX5KMT2ATSHR
SCHEMBL14729331 0.75 POLB (0.39) CYP1A2POLBALOX5KMT2ATSHR
SCHEMBL395290 0.75 CYP1A2 (0.61) CYP1A2KMT2ATSHRPAML3MBTL1
SCHEMBL13840850 0.74 GABRP (0.44) CYP1A2FOLH1KDM4C
SCHEMBL16465237 0.73 EPHX2 (0.59) CYP1A2POLBKMT2ATSHRPGR
SCHEMBL16465239 0.73 EPHX2 (0.59) CYP1A2POLBKMT2ATSHRPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 WO disclosed