Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.70 |
| ▸ | ESR1 | P03372 | 5/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.70 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.53 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13473685 | 0.88 | APP (0.48) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL1181642 | 0.83 | APP (1.00) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL15380796 | 0.80 | APP (0.94) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL4778599 | 0.80 | APP (0.94) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL14376616 | 0.77 | HSD17B1 (0.42) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL18020144 | 0.76 | HSD17B1 (0.48) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL12708064 | 0.76 | SNCA (0.50) | APPESR1ESR2 | |
| SCHEMBL13335779 | 0.74 | APP (0.81) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL12700333 | 0.74 | — | — | |
| SCHEMBL4444739 | 0.73 | APP (0.70) | APPESR1ESR2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928822-B1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2013-02-27 | — | — | EP | disclosed |