Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.94 |
| ▸ | ESR1 | P03372 | 4/20 | 0.94 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.94 |
| ▸ | HSD17B1 | P14061 | 8/20 | 0.68 |
| ▸ | HSD17B2 | P37059 | 8/20 | 0.68 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778599 | 1.00 | APP (0.94) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL1181642 | 0.97 | APP (1.00) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL15384801 | 0.89 | APP (0.74) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL13335779 | 0.87 | APP (0.81) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL12973224 | 0.85 | APP (0.77) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL12973258 | 0.85 | APP (1.00) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL27937503 | 0.83 | APP (0.65) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL1180468 | 0.82 | HSD17B1 (1.00) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL14156943 | 0.82 | MEN1 (0.68) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL14729649 | 0.80 | APP (0.70) | APPESR1ESR2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9716229-B2 | Polymer networks | UNIVERSITY OF HULL (GB) | 2017-07-25 | — | — | US | disclosed |
| EP-2665795-B1 | POLYMER NETWORKS | UNIV HULL (GB) | 2016-05-25 | — | — | EP | disclosed |
| EP-2665795-B1 | POLYMER NETWORKS | UNIV HULL (GB) | 2016-05-25 | — | — | EP | disclosed |
| US-20130299805-A1 | POLYMER NETWORKS | UNIVERSITY OF HULL (GB) | 2013-11-14 | — | — | US | disclosed |
| US-20130299805-A1 | POLYMER NETWORKS | UNIVERSITY OF HULL (GB) | 2013-11-14 | — | — | US | disclosed |