Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14729714 | 0.85 | PTPN1 (0.50) | PTPN1PTPN6PTPN2RXRARXRB | |
| SCHEMBL14729703 | 0.81 | MRGPRX4 (0.43) | CYP11B1CYP11B2PTGER1CYP2C9PTPN1 | |
| SCHEMBL14719578 | 0.81 | CYP11B1 (0.44) | CYP11B1CYP11B2PTGER1CYP2C9TBXA2R | |
| SCHEMBL31387957 | 0.81 | CYP11B1 (0.44) | CYP11B1CYP11B2PTGER1CYP2C9TBXA2R | |
| SCHEMBL14729656 | 0.80 | MRGPRX4 (0.45) | PTPN1PTPN6PTPN2RXRARXRB | |
| SCHEMBL14729707 | 0.79 | SQOR (0.51) | CYP11B1CYP11B2PTGER1CYP19A1MEN1 | |
| SCHEMBL14719354 | 0.79 | CYP11B1 (0.38) | CYP11B1CYP11B2PTGER1CYP2C9TBXA2R | |
| SCHEMBL14729682 | 0.76 | RXRA (0.47) | CYP11B1CYP11B2PTGER1CYP2C9PTPN1 | |
| SCHEMBL14729677 | 0.76 | SMN1; SMN2 (0.45) | PTGER1MEN1ALDH1A1KMT2A | |
| SCHEMBL14729755 | 0.76 | MEN1 (0.46) | RXRARXRBRXRGMRGPRX4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130052281-A1 | NOVEL COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130052281-A1 | NOVEL COMPOUNDS | ABCG2, F12, UGT1A1 | CYP11B1 51/4885CYP11B2 43/4885PTGER1 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.