Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SGK1 | O00141 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1473152 | 0.98 | IKBKB (0.38) | IKBKBPOLBGAAKMT2AEZH2 | |
| SCHEMBL1472982 | 0.79 | KMT2A (0.41) | KMT2AMEN1SGK1 | |
| SCHEMBL1471426 | 0.79 | MMP13 (0.43) | KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1471230 | 0.78 | KMT2A (0.40) | KMT2AMEN1SGK1 | |
| Hydrochloric Acid SCHEMBL1471477 | 0.78 | MMP13 (0.42) | KMT2AMEN1 | |
| SCHEMBL1471398 | 0.77 | SCD (0.45) | KMT2AEZH2 | |
| SCHEMBL1470890 | 0.77 | LMNA (0.43) | GAAKMT2AEZH2LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL1470860 | 0.76 | SCD (0.44) | KMT2AEZH2 | |
| Hydrochloric Acid SCHEMBL1470850 | 0.75 | LMNA (0.42) | GAAKMT2AEZH2LMNAMEN1 | |
| SCHEMBL21163541 | 0.75 | GAA (0.42) | POLBGAAKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215820-A1 | NOVEL ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | ANIONA APS (DK) | 2009-08-27 | — | — | US | claimed |
| US-7547788-B2 | Alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2009-06-16 | — | — | US | claimed |
| US-20070167487-A1 | Novel alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | ANIONA APS (DK) | 2007-07-19 | — | — | US | claimed |
| EP-1761493-A2 | ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2007-03-14 | — | — | EP | claimed |
| WO-2005123679-A2 | ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2005-12-29 | — | — | WO | claimed |
| US-20110086880-A1 | NOVEL ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | PETERS DAN | 2011-04-14 | — | — | US | disclosed |
| US-7915419-B2 | Alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2011-03-29 | — | — | US | disclosed |
| US-20090215820-A1 | NOVEL ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | ANIONA APS (DK) | 2009-08-27 | — | — | US | disclosed |
| US-7547788-B2 | Alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2009-06-16 | — | — | US | disclosed |
| US-20070167487-A1 | Novel alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | ANIONA APS (DK) | 2007-07-19 | — | — | US | disclosed |
| EP-1761493-A2 | ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005123679-A2 | ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215820-A1 | NOVEL ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | SLC18A2, SLC6A2, SLC18A3 | IKBKB 2707/4885POLB 1640/4885GAA 286/4885 |
| US-20070167487-A1 | Novel alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | SLC18A2, SLC6A2, SLC18A3 | IKBKB 2707/4885POLB 1640/4885GAA 286/4885 |
| US-20110086880-A1 | NOVEL ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | SLC18A2, SLC6A2, SLC18A3 | IKBKB 2707/4885POLB 1640/4885GAA 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.