Sugi Predict

Sugi Predict / Compounds / SCHEMBL14730233

SCHEMBL14730233

SCHEMBL14730233

C=C/C(C)=C\C=C(\F)C[C@H]1CN(c2ncc(C(=O)N(CC)C3CCN(c4nc(C(C)(F)F)no4)CC3)cn2)C[C@@H]1N

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 1/20 0.32
▸ ALOX5AP P20292 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14730298 0.86 ALOX5AP (0.34) GPR119ALOX5AP
SCHEMBL14730245 0.86 GPR119 (0.32) GPR119
SCHEMBL14730368 0.86 GPR119 (0.32) GPR119
SCHEMBL14730192 0.85 GPR119 (0.32) GPR119ALOX5AP
SCHEMBL14730246 0.83 GPR119 (0.32) GPR119
SCHEMBL14730302 0.83 ALOX5AP (0.33) GPR119ALOX5AP
SCHEMBL14730185 0.80 GPR119 (0.34) GPR119
SCHEMBL14730247 0.78 — —
SCHEMBL14730359 0.77 MCHR1 (0.36) GPR119ALOX5AP
SCHEMBL14730170 0.74 GPR119 (0.30) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013026587-A1 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS PROSIDION LIMITED (GB) 2013-02-28 — — WO disclosed