Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 13/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730360 | 0.94 | MCHR1 (0.36) | GPR119DPP4DPP7DPP8DPP9 | |
| SCHEMBL14730238 | 0.92 | DPP4 (0.40) | GPR119DPP4DPP7DPP8DPP9 | |
| SCHEMBL14730186 | 0.91 | GPR119 (0.36) | PDK2GPR119DPP4DPP7DPP8 | |
| SCHEMBL14730361 | 0.90 | GPR119 (0.35) | PDK2GPR119DPP4DPP7DPP8 | |
| SCHEMBL14730219 | 0.86 | PDK2 (0.36) | PDK2GPR119HDAC3HDAC4HDAC1 | |
| SCHEMBL14730184 | 0.85 | GPR119 (0.36) | GPR119DPP4DPP7DPP8DPP9 | |
| SCHEMBL14730284 | 0.84 | MCHR1 (0.36) | GPR119DPP4DPP7DPP8DPP9 | |
| SCHEMBL14730359 | 0.83 | MCHR1 (0.36) | GPR119DPP4DPP7DPP8DPP9 | |
| SCHEMBL14730183 | 0.82 | DPP4 (0.33) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL14730293 | 0.82 | DPP4 (0.32) | PDK2DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |