Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 8/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.33 |
| ▸ | TACR3 | P29371 | 5/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730248 | 0.94 | PDK2 (0.35) | MCHR1GPR119DPP4DPP8DPP9 | |
| SCHEMBL14730238 | 0.92 | DPP4 (0.40) | GPR119DPP4DPP8DPP9KCNH2 | |
| SCHEMBL14730184 | 0.92 | GPR119 (0.36) | MCHR1GPR119DPP4DPP8DPP9 | |
| SCHEMBL14730284 | 0.90 | MCHR1 (0.36) | MCHR1GPR119DPP4DPP8DPP9 | |
| SCHEMBL14730359 | 0.89 | MCHR1 (0.36) | MCHR1GPR119DPP4DPP8DPP9 | |
| SCHEMBL14730244 | 0.88 | MCHR1 (0.35) | MCHR1GPR119DPP4DPP8DPP9 | |
| SCHEMBL14730186 | 0.86 | GPR119 (0.36) | MCHR1GPR119DPP4DPP8DPP9 | |
| SCHEMBL14730371 | 0.84 | MCHR1 (0.35) | MCHR1GPR119DPP4DPP8DPP9 | |
| SCHEMBL14730361 | 0.84 | GPR119 (0.35) | GPR119DPP4DPP8KCNH2DPP7 | |
| SCHEMBL14730358 | 0.82 | DPP4 (0.37) | GPR119DPP4DPP8DPP9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |