SCHEMBL14730296 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	NTRK1	P04629	7/20	0.38

▸	RET	P07949	7/20	0.35

▸	MCHR1	Q99705	1/20	0.34

▸	F2R	P25116	1/20	0.33

▸	JAK2	O60674	1/20	0.33

▸	HDAC3	O15379	1/20	0.33

▸	HDAC2	Q92769	1/20	0.33

▸	NPY5R	Q15761	3/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14730345	0.90	NTRK1 (0.40)	NTRK1RETMCHR1
SCHEMBL14730294	0.85	NTRK1 (0.42)	NTRK1RETMCHR1F2RNPY5R
SCHEMBL14723500	0.85	NTRK1 (0.42)	NTRK1RETMCHR1F2RNPY5R
SCHEMBL14730278	0.84	NTRK1 (0.43)	NTRK1RETMCHR1F2R
SCHEMBL14722263	0.84	NTRK1 (0.43)	NTRK1RETMCHR1F2R
SCHEMBL14730347	0.83	NTRK1 (0.36)	NTRK1MCHR1F2RHDAC3HDAC2
SCHEMBL1720753	0.82	NTRK1 (0.40)	NTRK1RETMCHR1F2RNPY5R
SCHEMBL609468	0.82	NTRK1 (0.40)	NTRK1RETMCHR1F2RNPY5R
SCHEMBL10058396	0.82	NTRK1 (0.40)	NTRK1RETMCHR1F2RNPY5R
SCHEMBL609745	0.79	RET (0.44)	NTRK1RETMCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013026587-A1	1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS	PROSIDION LIMITED (GB)	2013-02-28	—	—	WO	disclosed