Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20375350 | 0.83 | FGFR2 (0.47) | SIRT1FGFR2SRD5A2ALDH1A1LMNA | |
| SCHEMBL14557909 | 0.82 | FGFR2 (0.38) | SIRT1FGFR2SRD5A2ALDH1A1LMNA | |
| SCHEMBL14364636 | 0.80 | ALDH1A1 (0.33) | FGFR2ALDH1A1LMNAALOX15APEX1 | |
| SCHEMBL10066813 | 0.80 | CASP1 (0.36) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL14546135 | 0.80 | ALDH1A1 (0.34) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL10066820 | 0.79 | PPARG (0.32) | ALDH1A1LMNAALOX15MAPK1HSD17B10 | |
| SCHEMBL12807627 | 0.79 | ALDH1A1 (0.33) | FGFR2ALDH1A1LMNAALOX15MAPK1 | |
| SCHEMBL26546694 | 0.78 | FGFR2 (0.44) | SIRT1FGFR2SRD5A2ALDH1A1LMNA | |
| SCHEMBL14557906 | 0.78 | ELANE (0.33) | FGFR2ALDH1A1LMNAALOX15MAPK1 | |
| SCHEMBL10066823 | 0.77 | CASP1 (0.35) | ALDH1A1LMNAALOX15APEX1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130052564-A1 | POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY, AND SOLID POLYMER FUEL CELL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-28 | — | — | US | disclosed |