Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | WRN | Q14191 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19144095 | 0.85 | EGLN2 (0.50) | EGLN2PGRALDH1A1TRPV4 | |
| SCHEMBL8410428 | 0.82 | ALDH1A1 (0.44) | EGLN2ABCG2ALDH1A1SLC22A12 | |
| SCHEMBL546977 | 0.79 | SLC22A12 (0.56) | ARSLC22A12CNR2 | |
| SCHEMBL3173181 | 0.79 | GRM4 (0.48) | GRM4ABCG2BLMWRNPGR | |
| SCHEMBL241795 | 0.78 | RAB9A (0.46) | ALDH1A1SLC22A12 | |
| SCHEMBL8410032 | 0.78 | SLC22A12 (0.51) | GRM4BLMWRNALDH1A1TRPV4 | |
| SCHEMBL21844923 | 0.77 | GRM4 (0.47) | GRM4ABCG2BLMWRNPGR | |
| SCHEMBL19190440 | 0.77 | GRM4 (0.50) | GRM4ABCG2BLMWRNPGR | |
| SCHEMBL897882 | 0.77 | GRM4 (0.47) | GRM4ABCG2BLMWRNPGR | |
| SCHEMBL7230699 | 0.76 | GRM4 (0.46) | GRM4ABCG2BLMWRNPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712139-A1 | ANTI-HBV TETRAHYDROISOXAZOLO[4,3-C]PYRIDINE COMPOUNDS | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |
| WO-2019154343-A1 | CAPSID PROTEIN ASSEMBLY INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 正大天晴药业集团股份有限公司 | 2019-08-15 | — | — | WO | disclosed |
| WO-2013027196-A1 | SUBSTITUTED 2-ALKYL-1-OXO-N-PHENYL-3-HETEROARYL-1,2,3,4- TETRAHYDROISOQUINOLINE-4-CARBOXAMIDES FOR ANTIMALARIAL THERAPIES | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2013-02-28 | — | — | WO | disclosed |