Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18471342 | 0.88 | LMNA (0.63) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16312541 | 0.88 | LMNA (0.63) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7839495 | 0.87 | LMNA (0.61) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7839491 | 0.87 | LMNA (0.61) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7356638 | 0.85 | PRSS1 (0.56) | LMNAHPGDHDAC1ALDH1A1TP53 | |
| SCHEMBL12104795 | 0.84 | LMNA (0.67) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2786631 | 0.81 | LMNA (0.63) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6277 | 0.81 | LMNA (0.67) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL530337 | 0.81 | LMNA (0.67) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8108955 | 0.81 | LMNA (0.67) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053433-A1 | FATTY ACID DERIVATIVES AND ANALOGS OF DRUGS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053433-A1 | FATTY ACID DERIVATIVES AND ANALOGS OF DRUGS | FFAR2, FASN, FFAR4 | LMNA 1419/4885HPGD 599/4885HDAC1 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.