SCHEMBL14730772

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14730771	0.83	HCAR3 (0.54)	MAPK1KDM4EL3MBTL1ALDH1A1CYP2C9
	SCHEMBL1021132	0.83	MAPK1 (0.59)	MAPK1KDM4EL3MBTL1ALDH1A1CYP2C9
	SCHEMBL1713848	0.82	MAPK1 (0.57)	MAPK1KDM4EL3MBTL1ALDH1A1CYP2C9
	SCHEMBL14730851	0.82	NNMT (0.56)	KDM4EL3MBTL1ALDH1A1
	SCHEMBL25216018	0.81	MAPK1 (0.56)	MAPK1KDM4EL3MBTL1ALDH1A1CYP2C9
	SCHEMBL30516117	0.78	MAPK1 (0.53)	MAPK1KDM4EL3MBTL1ALDH1A1CYP2C9
	SCHEMBL840039	0.75	MAPK1 (0.49)	MAPK1KDM4EL3MBTL1ALDH1A1RAB9A
	SCHEMBL31434911	0.75	MAPK1 (0.49)	MAPK1KDM4EL3MBTL1ALDH1A1CYP2C9
	SCHEMBL25256850	0.75	MAPK1 (0.53)	MAPK1KDM4EL3MBTL1ALDH1A1CYP2C9
	SCHEMBL10153945	0.74	CA1 (0.59)	ALDH1A1CYP2C9POLBGAACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.