SCHEMBL14730774

SCHEMBL14730774

CCCCCCCCCCCCCCCC(CC(=O)OCC)C(C(=O)OCC)C(=O)OCC

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.41
GPR84 Q9NQS5 7/20 0.40
KMT2A Q03164 1/20 0.39
NAAA Q02083 1/20 0.38
DGKA P23743 1/20 0.38
FFAR1 O14842 1/20 0.38
CPB2 Q96IY4 1/20 0.37
MAPT P10636 2/20 0.37
LCK P06239 1/20 0.37
PPARD Q03181 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3392348 0.86 MGAM (0.41) KMT2AMAPT
SCHEMBL3392227 0.86 MGAM (0.41) KMT2AMAPT
SCHEMBL7505999 0.84 ZDHHC7 (0.44) ZDHHC7GPR84KMT2AFFAR1CPB2
SCHEMBL7509050 0.84 ZDHHC7 (0.44) ZDHHC7GPR84KMT2AFFAR1CPB2
SCHEMBL7204081 0.84 ZDHHC7 (0.49) ZDHHC7GPR84KMT2AFFAR1CPB2
SCHEMBL7512070 0.84 ZDHHC7 (0.44) ZDHHC7GPR84KMT2AFFAR1CPB2
SCHEMBL7779110 0.84 ZDHHC7 (0.49) ZDHHC7GPR84KMT2AFFAR1CPB2
SCHEMBL7509191 0.84 ZDHHC7 (0.43) ZDHHC7GPR84KMT2AFFAR1CPB2
SCHEMBL6829979 0.82 ZDHHC7 (0.42) ZDHHC7GPR84KMT2AFFAR1CPB2
SCHEMBL1479671 0.81 ZDHHC7 (0.39) ZDHHC7GPR84NAAADGKAFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130053433-A1 FATTY ACID DERIVATIVES AND ANALOGS OF DRUGS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130053433-A1 FATTY ACID DERIVATIVES AND ANALOGS OF DRUGS FFAR2, FASN, FFAR4 ZDHHC7 236/4885GPR84 613/4885KMT2A 3473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.