SCHEMBL6829979

SCHEMBL6829979

CCCCCC(CC)C(C(=O)OCC)C(=O)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.42
CA1 P00915 3/20 0.40
CA2 P00918 2/20 0.40
GPR84 Q9NQS5 5/20 0.38
FFAR1 O14842 1/20 0.38
CPB2 Q96IY4 1/20 0.38
MAPT P10636 2/20 0.37
TP53 P04637 1/20 0.37
LCK P06239 1/20 0.37
PPARD Q03181 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
FAAH O00519 1/20 0.37
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7512070 0.98 ZDHHC7 (0.44) ZDHHC7CA1CA2GPR84FFAR1
SCHEMBL7509050 0.98 ZDHHC7 (0.44) ZDHHC7CA1CA2GPR84FFAR1
SCHEMBL7505999 0.98 ZDHHC7 (0.44) ZDHHC7CA1CA2GPR84FFAR1
SCHEMBL7509155 0.94 CA2 (0.46) ZDHHC7CA1CA2CPB2MAPT
SCHEMBL7509191 0.90 ZDHHC7 (0.43) ZDHHC7CA1CA2GPR84FFAR1
SCHEMBL7779110 0.87 ZDHHC7 (0.49) ZDHHC7CA2GPR84FFAR1CPB2
SCHEMBL7204081 0.87 ZDHHC7 (0.49) ZDHHC7CA2GPR84FFAR1CPB2
SCHEMBL27513818 0.86 ALDH1A1 (0.39) ZDHHC7CA1CA2CPB2MAPT
SCHEMBL7506703 0.86 CA2 (0.44) ZDHHC7CA1CA2CPB2MAPT
SCHEMBL14730774 0.82 ZDHHC7 (0.41) ZDHHC7GPR84FFAR1CPB2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4015511-A1 OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS CARNEGIE MELLON UNIVERSITY (US) 2022-06-22 EP disclosed
EP-3353157-B1 OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS UNIV CARNEGIE MELLON (US) 2021-11-24 EP disclosed
WO-2004076425-A1 IMPROVED SYNTHESIS OF MACROCYCLIC TETRAAMIDO COMPOUNDS AND NEW METAL INSERTION PROCESS CARNEGIE MELLON UNIVERSITY (US) 2004-09-10 WO disclosed
EP-0914206-B1 LONG-LIVED HOMOGENOUS OXIDATION CATALYSTS UNIV CARNEGIE MELLON (US) 2002-12-11 EP disclosed