Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cianopramine SCHEMBL209730 | 0.84 | SLC6A4 (0.78) | SLC6A4HTR2ASLC6A2CHRM2CHRM1 | |
| SCHEMBL14723083 | 0.84 | SLC6A4 (0.55) | SLC6A4HTR2ASLC6A2CHRM2CHRM1 | |
| SCHEMBL14723391 | 0.84 | SLC6A4 (0.55) | SLC6A4HTR2ASLC6A2CHRM2CHRM1 | |
| SCHEMBL6961973 | 0.83 | HTR2A (0.68) | SLC6A4HTR2ASLC6A2CHRM2CHRM1 | |
| SCHEMBL6963720 | 0.80 | HTR2A (0.53) | SLC6A4HTR2ASLC6A2CHRM2CHRM1 | |
| SCHEMBL8195707 | 0.80 | HTR2A (0.70) | SLC6A4HTR2ASLC6A2CHRM2CHRM1 | |
| SCHEMBL23700750 | 0.79 | SLC6A4 (0.46) | SLC6A4HTR2ASLC6A2CHRM2CHRM1 | |
| SCHEMBL29833634 | 0.79 | SLC6A4 (0.46) | SLC6A4HTR2ASLC6A2CHRM2CHRM1 | |
| SCHEMBL14721753 | 0.79 | SLC6A4 (0.51) | SLC6A4HTR2ASLC6A2CHRM2CHRM1 | |
| SCHEMBL7168298 | 0.78 | HTR2A (0.66) | SLC6A4HTR2ASLC6A2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026455-A1 | PERMANENTLY POSITIVELY CHARGED ANTIDEPRESSANTS | AARHUS UNIVERSITET (DK) | 2013-02-28 | — | — | WO | disclosed |