Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14732922 | 0.93 | TGFBR1 (0.47) | PDE10ACYP1A2ALDH1A1HPGDNUDT1 | |
| SCHEMBL8779392 | 0.84 | PDE10A (0.46) | PDE10ACYP1A2ALDH1A1HPGDNUDT1 | |
| SCHEMBL14733019 | 0.80 | METAP1 (0.49) | TGFBR1MAPK14KMT2AMEN1RAB9A | |
| SCHEMBL14733018 | 0.80 | TGFBR1 (0.46) | TGFBR1MAPK14NOS3NOS1NOS2 | |
| SCHEMBL8779715 | 0.79 | MAPT (0.44) | PDE10ACYP1A2ALDH1A1HPGDNUDT1 | |
| SCHEMBL8884919 | 0.78 | PDE10A (0.62) | PDE10ACYP1A2ALDH1A1HPGDNUDT1 | |
| SCHEMBL8779730 | 0.77 | PDE10A (0.40) | PDE10ACYP1A2ALDH1A1HPGDNUDT1 | |
| SCHEMBL8872433 | 0.76 | PDE10A (0.49) | PDE10ACYP1A2ALDH1A1HPGDNUDT1 | |
| SCHEMBL14732960 | 0.73 | CYP1A2 (0.42) | PDE10ACYP1A2GPR3KCNH2L3MBTL1 | |
| SCHEMBL8779683 | 0.71 | GRM5 (0.53) | PDE10ACYP1A2ALDH1A1HPGDNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |