Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 16/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14732922 | 0.88 | TGFBR1 (0.47) | TGFBR1MAPK14CCR1CCR8 | |
| SCHEMBL14733019 | 0.85 | METAP1 (0.49) | TGFBR1MAPK14CCR1CCR8MEN1 | |
| SCHEMBL14733012 | 0.80 | PDE10A (0.47) | TGFBR1MAPK14MEN1RAB9AKMT2A | |
| SCHEMBL14732969 | 0.78 | CCR1 (0.64) | TGFBR1CCR1CCR8NOS3NOS1 | |
| SCHEMBL14732929 | 0.78 | CCR1 (0.41) | TGFBR1MAPK14CCR1CCR8 | |
| SCHEMBL14732901 | 0.77 | CCR1 (0.50) | TGFBR1CCR1CCR8NOS3NOS1 | |
| SCHEMBL14733132 | 0.77 | CCR1 (0.43) | TGFBR1CCR1CCR8NOS3NOS1 | |
| SCHEMBL9607741 | 0.77 | BRD4 (0.40) | MEN1RAB9AKMT2A | |
| SCHEMBL14733134 | 0.74 | CCR1 (0.50) | TGFBR1MAPK14CCR1CCR8NOS1 | |
| SCHEMBL14733149 | 0.73 | CCR1 (0.42) | TGFBR1MAPK14CCR1CCR8RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |