SCHEMBL14733138

SCHEMBL14733138

CO/N=C(\C)c1cccc(CCCc2cccc(-c3cccc(SC)n3)n2)n1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14733059 0.86 CCR1 (0.42) KCNH2
SCHEMBL14732923 0.86 CCR1 (0.42) KCNH2
SCHEMBL14733136 0.84
SCHEMBL14733165 0.82 IRAK4 (0.35) KCNH2
SCHEMBL14732958 0.81 KDM4E (0.41)
SCHEMBL14732961 0.79 KCNH2 (0.36) KCNH2
SCHEMBL14733133 0.77 FFAR1 (0.36)
SCHEMBL14733014 0.76 GRM5 (0.34)
SCHEMBL16164122 0.76 KCNH2 (0.36) KCNH2
SCHEMBL14732962 0.76 KCNH2 (0.41) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013026866-A2 NOVEL MICROBIOCIDES SYNGENTA PARTICIPATIONS AG (CH) 2013-02-28 WO disclosed