Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733034 | 0.85 | CCR1 (0.47) | IRAK4KCNH2CYP4F2CYP4A11BRD4 | |
| SCHEMBL14733138 | 0.82 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL14732976 | 0.79 | NOS2 (0.42) | KCNH2 | |
| SCHEMBL6187845 | 0.79 | ALDH1A1 (0.44) | IRAK4ALDH1A1P2RX7 | |
| SCHEMBL14733136 | 0.77 | — | — | |
| SCHEMBL8662483 | 0.75 | KCNH2 (0.43) | IRAK4KCNH2CYP4F2CYP4A11BRD4 | |
| SCHEMBL14732978 | 0.73 | LMNA (0.41) | NPSR1ALDH1A1 | |
| SCHEMBL10556900 | 0.72 | ALDH1A1 (0.50) | IRAK4ALDH1A1P2RX7ECE1 | |
| SCHEMBL6898745 | 0.71 | KCNH2 (0.46) | IRAK4KCNH2BRD4NPSR1ALDH1A1 | |
| SCHEMBL4859332 | 0.71 | NPSR1 (0.43) | IRAK4KCNH2BRD4NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |