Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR8 | P51685 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721128 | 0.86 | CCR1 (0.60) | CCR1CCR8GRM5TGFBR1CYP2A6 | |
| SCHEMBL12497117 | 0.82 | CCR1 (0.56) | CCR1CCR8GRM5TGFBR1CYP2A6 | |
| SCHEMBL14733154 | 0.77 | CCR1 (0.48) | CCR1CCR8TGFBR1CYP2A6METAP2 | |
| SCHEMBL9678508 | 0.75 | POLB (0.43) | CCR1CCR8GRM5TGFBR1MAPK14 | |
| SCHEMBL14733146 | 0.74 | CCR1 (0.42) | CCR1CCR8GRM5TGFBR1METAP2 | |
| SCHEMBL15470590 | 0.74 | CCR1 (0.65) | CCR1CCR8GRM5TGFBR1CYP2A6 | |
| SCHEMBL14733153 | 0.72 | CCR1 (0.52) | CCR1CCR8GRM5TGFBR1CYP2A6 | |
| SCHEMBL14732973 | 0.72 | CCR1 (0.70) | CCR1CCR8GRM5TGFBR1CYP2A6 | |
| SCHEMBL24156108 | 0.72 | MAPT (0.41) | NOS3NOS2 | |
| SCHEMBL18482809 | 0.70 | CCR1 (0.65) | CCR1CCR8GRM5TGFBR1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |