Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14732901 | 0.89 | CCR1 (0.50) | CCR1CCR8TGFBR1GRM5NOS1 | |
| SCHEMBL14733156 | 0.83 | GRM5 (0.49) | CCR1CCR8TGFBR1GRM5KCNH2 | |
| SCHEMBL14733132 | 0.83 | CCR1 (0.43) | CCR1CCR8TGFBR1GRM5NOS1 | |
| SCHEMBL14733135 | 0.83 | LMNA (0.44) | CCR1CCR8TGFBR1GRM5NOS1 | |
| SCHEMBL14732969 | 0.81 | CCR1 (0.64) | CCR1CCR8TGFBR1GRM5NOS1 | |
| SCHEMBL14733147 | 0.81 | CCR1 (0.41) | CCR1CCR8TGFBR1NOS1NOS2 | |
| SCHEMBL14733005 | 0.79 | GRM5 (0.44) | CCR1CCR8TGFBR1GRM5FFAR1 | |
| SCHEMBL14733134 | 0.77 | CCR1 (0.50) | CCR1CCR8TGFBR1KDM4EGRM5 | |
| SCHEMBL14732990 | 0.77 | NOS2 (0.49) | CCR1CCR8TGFBR1NOS1NOS2 | |
| SCHEMBL10369437 | 0.76 | CTSK (0.38) | KDM4ENOS1NOS2KCNH2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |