Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31638154 | 0.91 | MAPT (0.47) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL1646319 | 0.91 | MAPT (0.47) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL14732970 | 0.85 | CCR1 (0.48) | LMNAKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL14732977 | 0.83 | KMT2A (0.44) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL14732978 | 0.81 | LMNA (0.41) | SMN1; SMN2LMNAKMT2AMEN1CYP1A2 | |
| SCHEMBL1135252 | 0.79 | ALDH1A1 (0.48) | LMNAKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL14677477 | 0.77 | KMT2A (0.47) | MAPTLMNAKMT2AMEN1CYP1A2 | |
| SCHEMBL22070548 | 0.77 | KMT2A (0.47) | MAPTLMNAKMT2AMEN1CYP1A2 | |
| SCHEMBL22940127 | 0.77 | PRMT5 (0.49) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL10896384 | 0.76 | CYP4F2 (0.50) | MAPTSMN1; SMN2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |