SCHEMBL14733228

SCHEMBL14733228

CCOC(=O)CCOC(=O)OCC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
GAA P10253 2/20 0.50
MGAM O43451 1/20 0.50
SI P14410 1/20 0.50
MGAM2 Q2M2H8 1/20 0.50
SOAT1 P35610 1/20 0.50
CYP1A2 P05177 1/20 0.50
TRPA1 O75762 1/20 0.46
CYP4F2 P78329 3/20 0.43
CYP4A11 Q02928 3/20 0.43
LMNA P02545 2/20 0.40
HSD17B10 Q99714 1/20 0.40
NR1I2 O75469 1/20 0.40
PGR P06401 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
PTGS2 P35354 1/20 0.40
PDE4D Q08499 1/20 0.40
DGKA P23743 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
POLB P06746 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18050394 0.86 CYP1A2 (0.57) ALDH1A1GAAMGAMSIMGAM2
SCHEMBL10597810 0.83 DGKA (0.53) ALDH1A1GAACYP1A2CYP4F2CYP4A11
SCHEMBL8458595 0.82 ALDH1A1 (0.56) ALDH1A1GAAMGAMSIMGAM2
SCHEMBL19598979 0.82 ALDH1A1 (0.81) ALDH1A1GAAMGAMSIMGAM2
SCHEMBL1718009 0.82 ALDH1A1 (0.81) ALDH1A1GAAMGAMSIMGAM2
SCHEMBL2909701 0.81 ALDH1A1 (0.59) ALDH1A1GAAMGAMSIMGAM2
SCHEMBL10873279 0.81 ALDH1A1 (0.62) ALDH1A1GAAMGAMSIMGAM2
SCHEMBL10924595 0.81 GAA (0.50) ALDH1A1GAAMGAMSIMGAM2
SCHEMBL4444616 0.81 GAA (0.50) ALDH1A1GAAMGAMSIMGAM2
SCHEMBL15270166 0.81 ALDH1A1 (0.62) ALDH1A1GAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406541-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2020-03-31 CN disclosed
EP-3268397-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2019-04-17 EP disclosed
US-10030082-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-07-24 US disclosed
US-20180057621-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-03-01 US disclosed
EP-3268397-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2018-01-17 EP disclosed
WO-2016142335-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2016-09-15 WO disclosed
US-20130052543-A1 SECONDARY BATTERY, ELECTROLYTIC SOLUTION, BATTERY PACK, ELECTRONIC DEVICE, AND ELECTRICAL VEHICLE SONY CORPORATION (JP) 2013-02-28 US disclosed
US-20130052543-A1 SECONDARY BATTERY, ELECTROLYTIC SOLUTION, BATTERY PACK, ELECTRONIC DEVICE, AND ELECTRICAL VEHICLE SONY CORPORATION (JP) 2013-02-28 US disclosed