SCHEMBL14733306

SCHEMBL14733306

Cc1ccc(-c2c(-c3ccccc3)cc(-c3ccc(-c4cc(-c5ccccc5)c(-c5ccc(N)cc5)c(-c5ccccc5)c4)cc3)cc2-c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.52
CYP3A4 P08684 1/20 0.52
TAAR1 Q96RJ0 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
HPRT1 P00492 1/20 0.51
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
ACHE P22303 1/20 0.45
NPC1 O15118 5/20 0.43
RAB9A P51151 5/20 0.43
NTSR1 P30989 1/20 0.43
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
RCE1 Q9Y256 1/20 0.41
KDM4E B2RXH2 2/20 0.40
POLB P06746 1/20 0.40
PPARG P37231 1/20 0.40
MCL1 Q07820 1/20 0.40
NR2E3 Q9Y5X4 1/20 0.40
NCOR2 Q9Y618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14733303 1.00 HSD17B10 (0.52) HSD17B10CYP3A4TAAR1TDP1HPRT1
SCHEMBL20262955 0.91 HSD17B10 (0.62) HSD17B10CYP3A4TAAR1TDP1MEN1
SCHEMBL22898970 0.85 TDP1 (0.65) HSD17B10CYP3A4TAAR1TDP1HPRT1
SCHEMBL13448470 0.85 TDP1 (0.65) HSD17B10CYP3A4TAAR1TDP1HPRT1
SCHEMBL22898969 0.84 TAAR1 (0.54) HSD17B10CYP3A4TAAR1TDP1HPRT1
SCHEMBL14733298 0.83 TDP1 (0.61) HSD17B10CYP3A4TAAR1TDP1MEN1
SCHEMBL12957685 0.82 HSD17B10 (0.60) HSD17B10CYP3A4TAAR1TDP1HPRT1
SCHEMBL13447737 0.82 HSD17B10 (0.60) HSD17B10CYP3A4TAAR1TDP1HPRT1
Biphenyl SCHEMBL9396267 0.81 TDP1 (0.70) HSD17B10CYP3A4TAAR1TDP1MEN1
SCHEMBL500204 0.81 ALDH1A1 (0.47) HSD17B10CYP3A4TAAR1TDP1HPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130053513-A1 LIQUID CRYSTAL ALIGNMENT AGENT, AND LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT FORMED FROM THE LIQUID CRYSTAL ALIGNMENT AGENT CHI MEI CORPORATION (TW) 2013-02-28 US disclosed