Biphenyl

Biphenyl

SCHEMBL9396267

Cc1ccc(N)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.70
CYP3A4 P08684 3/20 0.70
HSD17B10 Q99714 2/20 0.70
TAAR1 Q96RJ0 1/20 0.70
ACHE P22303 2/20 0.68
TEAD4 Q15561 1/20 0.52
ALDH1A1 P00352 6/20 0.50
MAPT P10636 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
TSHR P16473 2/20 0.50
POLB P06746 2/20 0.50
TP53 P04637 1/20 0.50
LMNA P02545 1/20 0.50
ALOX12 P18054 1/20 0.50
HPGD P15428 4/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
KDM4E B2RXH2 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13448470 0.91 TDP1 (0.65) TDP1CYP3A4HSD17B10TAAR1ACHE
SCHEMBL22898970 0.91 TDP1 (0.65) TDP1CYP3A4HSD17B10TAAR1ACHE
Benzidine SCHEMBL27996781 0.90 TDP1 (0.70) TDP1CYP3A4HSD17B10TAAR1ACHE
Benzidine SCHEMBL27889001 0.90 TDP1 (0.70) TDP1CYP3A4HSD17B10TAAR1ACHE
Aniline SCHEMBL10391735 0.89 ACHE (0.77) TDP1CYP3A4HSD17B10TAAR1ACHE
Benzene SCHEMBL28201085 0.89 ACHE (0.87) TDP1CYP3A4HSD17B10TAAR1ACHE
SCHEMBL14733298 0.88 TDP1 (0.61) TDP1CYP3A4HSD17B10TAAR1ACHE
Benzidine SCHEMBL27573076 0.87 TDP1 (0.67) TDP1CYP3A4HSD17B10TAAR1ACHE
SCHEMBL22795321 0.87 MEN1 (0.63) TDP1CYP3A4HSD17B10TAAR1ACHE
SCHEMBL13447737 0.87 HSD17B10 (0.60) TDP1CYP3A4HSD17B10TAAR1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3078717-B1 PHOTOBASE GENERATOR SAN APRO LTD (JP) 2020-05-20 EP disclosed
US-9933701-B2 Photobase generator SAN APRO LTD. (JP) 2018-04-03 US disclosed
US-9698352-B2 Amine compound and use thereof TOSOH CORPORATION (JP) 2017-07-04 US disclosed
EP-2902391-B1 NOVEL AMINE COMPOUND AND USE THEREOF TOSOH CORP (JP) 2017-03-08 EP disclosed
US-20160299429-A1 PHOTOBASE GENERATOR SAN APRO LTD. (JP) 2016-10-13 US disclosed
EP-3078717-A1 PHOTOBASE GENERATOR San-Apro Limited (JP) 2016-10-12 EP disclosed
CN-106030417-A Photosensitizing chemically amplified resist material, method for forming pattern using same, semiconductor device, mask for lithography, and template for nanoimprinting 东京毅力科创株式会社 2016-10-12 CN disclosed
EP-2980180-A1 PHOTOBASE GENERATOR San-Apro Ltd. (JP) 2016-02-03 EP disclosed
US-20160009737-A1 PHOTOBASE GENERATOR SAN-APRO LTD. (JP) 2016-01-14 US disclosed
US-20150243901-A1 NOVEL AMINE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2015-08-27 US disclosed
EP-2902391-A1 NOVEL AMINE COMPOUND AND USE THEREOF Tosoh Corporation (JP) 2015-08-05 EP disclosed
US-5330866-A Photosensitive member comprising an amino compound MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1994-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160299429-A1 PHOTOBASE GENERATOR RER1, ARL1, ARF1 TDP1 2304/4885CYP3A4 4130/4885HSD17B10 2577/4885
US-20150243901-A1 NOVEL AMINE COMPOUND AND USE THEREOF DRD1, MLLT1, DRD4 TDP1 2203/4885CYP3A4 1973/4885HSD17B10 1000/4885
US-20160009737-A1 PHOTOBASE GENERATOR PSMC6, ARCN1, CRY1 TDP1 1874/4885CYP3A4 3431/4885HSD17B10 1205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.