SCHEMBL14733734

SCHEMBL14733734

c1cc(-c2ccc3c(c2)c2ccccc2n3-c2cccc(-c3cccc4c3oc3c(-c5cccc(-n6c7ccccc7c7cc(-c8cccc(-n9c%10ccccc%10c%10ccccc%109)c8)ccc76)c5)cccc34)c2)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALOX5 P09917 1/20 0.41
PRKDC P78527 12/20 0.36
EDNRB P24530 1/20 0.34
EDNRA P25101 1/20 0.34
ALDH1A1 P00352 3/20 0.33
PIK3CD O00329 2/20 0.33
PIK3CA P42336 2/20 0.33
PIK3CB P42338 2/20 0.33
PIK3CG P48736 2/20 0.33
BRD4 O60885 2/20 0.33
BRD2 P25440 2/20 0.33
BRD3 Q15059 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GGPS1 O95749 1/20 0.33
PDE2A O00408 1/20 0.33
PIK3C2A O00443 1/20 0.33
PIK3R2 O00459 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15988960 0.96 KDM4E (0.45) KDM4EATML3MBTL1ALOX5PRKDC
SCHEMBL21578762 0.95 PRKDC (0.41) KDM4EATML3MBTL1ALOX5PRKDC
SCHEMBL781231 0.94 KDM4E (0.40) KDM4EATML3MBTL1ALOX5PRKDC
SCHEMBL13829570 0.93 KDM4E (0.44) KDM4EATML3MBTL1ALOX5PRKDC
SCHEMBL5028208 0.93 KDM4E (0.47) KDM4EATML3MBTL1ALOX5PRKDC
SCHEMBL13830074 0.92 ALOX5 (0.52) KDM4EATML3MBTL1ALOX5PRKDC
SCHEMBL16390630 0.92 KDM4E (0.41) KDM4EATML3MBTL1ALOX5PRKDC
SCHEMBL10165765 0.92 KDM4E (0.49) KDM4EATML3MBTL1ALOX5PRKDC
SCHEMBL10038519 0.92 KDM4E (0.51) KDM4EATML3MBTL1ALOX5PRKDC
SCHEMBL18020783 0.91 KDM4E (0.40) KDM4EATML3MBTL1ALOX5PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 US disclosed
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 US disclosed
US-9780322-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-10-03 US disclosed
US-9780322-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-10-03 US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-20150053949-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-02-26 US disclosed
US-20150053949-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-02-26 US disclosed
US-20140339529-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2014-11-20 US disclosed
US-20140296476-A1 PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES PROLYNX LLC 2014-10-02 US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140296476-A1 PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES ABCB1, ABCB11, DNPEP KDM4E 2898/4885ATM 4006/4885L3MBTL1 4082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.