SCHEMBL14733744

SCHEMBL14733744

c1ccc(-c2cc(-c3ccc4oc5ccc(-n6c7ccccc7c7ccccc76)cc5c4c3)cc(-c3ccc4oc5c(-c6ccccc6)cccc5c4c3)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.41
PLA2G2A P14555 4/20 0.37
PLA2G4A P47712 4/20 0.37
PLA2G10 O15496 1/20 0.37
PRKDC P78527 6/20 0.36
KDM4E B2RXH2 3/20 0.35
PIM1 P11309 2/20 0.35
CSNK2A2 P19784 2/20 0.35
CSNK2B P67870 2/20 0.35
PIM3 Q86V86 2/20 0.35
PIM2 Q9P1W9 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 3/20 0.34
PIK3CD O00329 2/20 0.34
PIK3CA P42336 2/20 0.34
PIK3CB P42338 2/20 0.34
PIK3CG P48736 2/20 0.34
BRD4 O60885 2/20 0.34
BRD2 P25440 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17057192 0.94 ALOX5 (0.46) ALOX5PLA2G2APLA2G4APLA2G10PRKDC
SCHEMBL17166693 0.94 ALOX5 (0.43) ALOX5PLA2G2APLA2G4APLA2G10PRKDC
SCHEMBL20097818 0.93 ALOX5 (0.43) ALOX5PLA2G2APLA2G4APLA2G10PRKDC
SCHEMBL18265970 0.93 ALOX5 (0.43) ALOX5PLA2G2APLA2G4APLA2G10PRKDC
SCHEMBL17228745 0.93 ALOX5 (0.44) ALOX5PLA2G2APLA2G4APLA2G10PRKDC
SCHEMBL14733816 0.92 ALOX5 (0.40) ALOX5PLA2G2APLA2G4APLA2G10PRKDC
SCHEMBL16573892 0.92 ALOX5 (0.50) ALOX5PLA2G2APLA2G4APLA2G10PRKDC
SCHEMBL23505132 0.92 ALOX5 (0.44) ALOX5PRKDCKDM4EPIM1CSNK2A2
SCHEMBL18266066 0.91 ALOX5 (0.47) ALOX5PLA2G2APLA2G4APLA2G10PRKDC
SCHEMBL2628388 0.91 ALOX5 (0.44) ALOX5PLA2G2APLA2G4APLA2G10PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 US disclosed
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 US disclosed
US-9780322-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-10-03 US disclosed
US-9780322-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-10-03 US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-20150053949-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-02-26 US disclosed
US-20150053949-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-02-26 US disclosed
US-20140339529-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2014-11-20 US disclosed
US-20140296476-A1 PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES PROLYNX LLC 2014-10-02 US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140296476-A1 PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES ABCB1, ABCB11, DNPEP ALOX5 2572/4885PLA2G2A 2000/4885PLA2G4A 1692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.