SCHEMBL14733746

SCHEMBL14733746

c1ccc(-c2cccc(-n3c4ccccc4c4cc(-c5ccc6oc7ccc(-n8c9ccccc9c9ccccc98)cc7c6c5)ccc43)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.44
KDM4E B2RXH2 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PLA2G2A P14555 4/20 0.40
PLA2G4A P47712 4/20 0.40
PLA2G10 O15496 1/20 0.39
TSPO P30536 2/20 0.38
PRKDC P78527 3/20 0.37
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36
PGR P06401 1/20 0.35
HDAC4 P56524 1/20 0.35
FAAH O00519 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HSP90AA1 P07900 1/20 0.34
PKM P14618 1/20 0.34
HTT P42858 1/20 0.34
MGLL Q99685 1/20 0.34
RAC2 P15153 1/20 0.34
RAC3 P60763 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24303628 1.00 ATM (0.44) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL16482382 1.00 ATM (0.44) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL18265963 1.00 ATM (0.44) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL18265992 1.00 ATM (0.44) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL14867957 1.00 ATM (0.44) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL17249477 0.99 ATM (0.42) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL14733873 0.99 ATM (0.42) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL17166733 0.99 ATM (0.42) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL21481465 0.97 KDM4E (0.41) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL15964297 0.97 KDM4E (0.41) ATMKDM4EL3MBTL1PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 US disclosed
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 US disclosed
US-9780322-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-10-03 US disclosed
US-9780322-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-10-03 US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-20150053949-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-02-26 US disclosed
US-20150053949-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-02-26 US disclosed
US-20140339529-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2014-11-20 US disclosed
US-20140296476-A1 PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES PROLYNX LLC 2014-10-02 US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140296476-A1 PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES ABCB1, ABCB11, DNPEP ATM 4006/4885KDM4E 2898/4885L3MBTL1 4082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.