SCHEMBL17249477

SCHEMBL17249477

c1ccc(-c2cccc(-c3cccc(-c4ccc(-c5ccc6c(c5)c5ccccc5n6-c5ccc6oc7ccc(-c8cccc(-n9c%10ccccc%10c%10cc(-c%11cccc(-c%12cccc(-c%13ccccc%13)c%12)c%11)ccc%109)c8)cc7c6c5)cc4)c3)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.42
KDM4E B2RXH2 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PLA2G2A P14555 4/20 0.40
PLA2G4A P47712 4/20 0.40
PLA2G10 O15496 1/20 0.40
PRKDC P78527 3/20 0.39
TSPO P30536 2/20 0.37
EDNRB P24530 1/20 0.35
EDNRA P25101 1/20 0.35
PGR P06401 1/20 0.35
HDAC4 P56524 1/20 0.34
FAAH O00519 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HSP90AA1 P07900 1/20 0.33
PKM P14618 1/20 0.33
HTT P42858 1/20 0.33
MGLL Q99685 1/20 0.33
RAC2 P15153 1/20 0.33
RAC3 P60763 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17166733 1.00 ATM (0.42) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL14733873 1.00 ATM (0.42) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL24303628 0.99 ATM (0.44) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL18265992 0.99 ATM (0.44) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL14867957 0.99 ATM (0.44) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL14733746 0.99 ATM (0.44) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL18265963 0.99 ATM (0.44) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL16482382 0.99 ATM (0.44) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL17166703 0.97 PLA2G2A (0.41) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL17166801 0.97 L3MBTL1 (0.46) ATMKDM4EL3MBTL1PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150322337-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-11-12 US disclosed
US-20150322337-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-11-12 US disclosed