Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12659529 | 0.65 | — | — | |
| SCHEMBL14034818 | 0.63 | — | — | |
| SCHEMBL18912155 | 0.60 | — | — | |
| SCHEMBL6905304 | 0.59 | — | — | |
| SCHEMBL6908645 | 0.58 | L3MBTL1 (0.33) | NOS3NOS2L3MBTL1SMN1; SMN2 | |
| SCHEMBL8817296 | 0.58 | — | — | |
| SCHEMBL19122782 | 0.57 | — | — | |
| SCHEMBL6911654 | 0.57 | LMNA (0.43) | NOS3NOS2NOS1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5311294 | 0.56 | — | — | |
| SCHEMBL6909848 | 0.56 | L3MBTL1 (0.38) | NOS3NOS2L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2269993-B1 | 2-AMINOQUINAZOLINE DERIVATIVE | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-02-27 | — | — | EP | disclosed |