Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14734632 | 0.88 | HTT (0.57) | HTTPOLBAPEX1TDP1NQO2 | |
| SCHEMBL14723015 | 0.85 | POLB (0.54) | HTTPOLBAPEX1TDP1HDAC3 | |
| SCHEMBL14723014 | 0.85 | POLB (0.54) | HTTPOLBAPEX1TDP1HDAC3 | |
| SCHEMBL14734620 | 0.84 | HTT (0.58) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL14734663 | 0.82 | HTT (0.58) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL14723111 | 0.81 | NQO2 (0.59) | HTTPOLBAPEX1TDP1HDAC3 | |
| SCHEMBL14723114 | 0.81 | NQO2 (0.59) | HTTPOLBAPEX1TDP1HDAC3 | |
| SCHEMBL4651518 | 0.80 | POLB (0.58) | HTTPOLBAPEX1TDP1NQO2 | |
| SCHEMBL4651509 | 0.80 | POLB (0.58) | HTTPOLBAPEX1TDP1NQO2 | |
| SCHEMBL28961925 | 0.80 | HTT (0.63) | HTTPOLBAPEX1TDP1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026691-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2013-02-28 | — | — | WO | disclosed |