Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.47 |
| ▸ | APP | P05067 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14734620 | 0.94 | HTT (0.58) | HTTPOLBAPEX1TDP1DNM1 | |
| SCHEMBL14734629 | 0.83 | HTT (0.53) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL14734632 | 0.82 | HTT (0.57) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL14734638 | 0.82 | HTT (0.56) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL14734645 | 0.82 | HTT (0.51) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL14605719 | 0.78 | TDP1 (0.43) | HTTPOLBAPEX1TDP1APP | |
| SCHEMBL13925724 | 0.77 | PRSS1 (0.49) | HTTPOLBAPEX1TDP1APP | |
| SCHEMBL9225800 | 0.77 | HTT (0.74) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL12214117 | 0.76 | HTT (0.68) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL9114019 | 0.76 | HTT (0.68) | HTTPOLBAPEX1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026691-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2013-02-28 | — | — | WO | disclosed |