Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13925724 | 0.91 | PRSS1 (0.49) | HTTPOLBAPEX1TDP1LTB4R | |
| SCHEMBL14734638 | 0.88 | HTT (0.56) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL14734620 | 0.87 | HTT (0.58) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL4652668 | 0.86 | HTT (0.53) | HTTPOLBAPEX1TDP1LTB4R | |
| SCHEMBL4652665 | 0.86 | HTT (0.53) | HTTPOLBAPEX1TDP1LTB4R | |
| SCHEMBL14605719 | 0.85 | TDP1 (0.43) | HTTPOLBAPEX1TDP1KMT2A | |
| SCHEMBL14734665 | 0.82 | RAB9A (0.44) | HTTPOLBAPEX1TDP1KMT2A | |
| SCHEMBL14734650 | 0.82 | MAPT (0.43) | HTTPOLBAPEX1TDP1KMT2A | |
| SCHEMBL14734663 | 0.82 | HTT (0.58) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL14722519 | 0.82 | HTT (0.53) | HTTPOLBAPEX1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026691-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2013-02-28 | — | — | WO | disclosed |