Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14734650 | 0.97 | MAPT (0.43) | MAPTRAB9ANPC1SMN1; SMN2NQO1 | |
| SCHEMBL14734665 | 0.91 | RAB9A (0.44) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13925724 | 0.89 | PRSS1 (0.49) | MAPTSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL14722270 | 0.87 | PTPN7 (0.44) | MAPTRAB9ASMN1; SMN2NQO1ALDH1A1 | |
| SCHEMBL14722324 | 0.87 | PTPN7 (0.44) | MAPTRAB9ASMN1; SMN2NQO1ALDH1A1 | |
| SCHEMBL15862121 | 0.87 | PTPN7 (0.44) | MAPTRAB9ASMN1; SMN2NQO1ALDH1A1 | |
| SCHEMBL15862122 | 0.87 | PTPN7 (0.44) | MAPTRAB9ASMN1; SMN2NQO1ALDH1A1 | |
| SCHEMBL14722269 | 0.87 | PTPN7 (0.44) | MAPTRAB9ASMN1; SMN2NQO1ALDH1A1 | |
| SCHEMBL14722323 | 0.87 | PTPN7 (0.44) | MAPTRAB9ASMN1; SMN2NQO1ALDH1A1 | |
| SCHEMBL14605719 | 0.86 | TDP1 (0.43) | MAPTSMN1; SMN2ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026691-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2013-02-28 | — | — | WO | disclosed |