Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14734650 | 0.95 | MAPT (0.43) | RAB9ANPC1MAPTSMN1; SMN2PRSS1 | |
| SCHEMBL14734651 | 0.92 | PRSS1 (0.40) | RAB9ANPC1PRSS1POLBKMT2A | |
| SCHEMBL14734680 | 0.91 | MAPT (0.43) | RAB9ANPC1MAPTSMN1; SMN2GAA | |
| SCHEMBL13925724 | 0.89 | PRSS1 (0.49) | MAPTSMN1; SMN2GAAPRSS1POLB | |
| SCHEMBL15862454 | 0.87 | MAPT (0.45) | RAB9ANPC1MAPTSMN1; SMN2GAA | |
| SCHEMBL15862453 | 0.87 | MAPT (0.45) | RAB9ANPC1MAPTSMN1; SMN2GAA | |
| SCHEMBL14734629 | 0.87 | HTT (0.53) | RAB9ANPC1MAPTSMN1; SMN2GAA | |
| SCHEMBL14734623 | 0.85 | PRSS1 (0.47) | RAB9ANPC1MAPTSMN1; SMN2GAA | |
| SCHEMBL14605719 | 0.84 | TDP1 (0.43) | MAPTSMN1; SMN2GAAPRSS1POLB | |
| SCHEMBL14734632 | 0.82 | HTT (0.57) | MAPTGAAPRSS1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026691-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2013-02-28 | — | — | WO | disclosed |