Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 17/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899368 | 0.84 | GRM5 (0.49) | GRM5MAP3K14 | |
| SCHEMBL3276812 | 0.84 | GRM5 (0.49) | GRM5MAP3K14 | |
| SCHEMBL990944 | 0.81 | GRM5 (0.58) | GRM5FPR2 | |
| SCHEMBL1906015 | 0.81 | GRM5 (0.58) | GRM5FPR2 | |
| SCHEMBL3802097 | 0.80 | GRM5 (0.42) | GRM5 | |
| SCHEMBL2842438 | 0.77 | GRM5 (0.43) | GRM5MAPT | |
| SCHEMBL2839746 | 0.77 | GRM5 (0.43) | GRM5MAPT | |
| SCHEMBL2838365 | 0.77 | GRM5 (0.43) | GRM5 | |
| SCHEMBL2841216 | 0.77 | GRM5 (0.43) | GRM5 | |
| SCHEMBL2813710 | 0.76 | GRM5 (0.54) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563934-A1 | PREDICTIVE MARKERS USEFUL IN THE TREATMENT OF FRAGILE X SYNDROME (FXS) | Novartis AG (CH) | 2013-03-06 | — | — | EP | disclosed |